Alcohol
What You Don't Know Can Harm You 
If you are like many Americans, you may drink alcohol occasionally. Or, like 
others, you may drink moderate amounts of alcohol on a more regular basis. If 
you are a woman or someone over the age of 65, this means that you have no more 
than one drink per day; if you are a man, this means that you have no more than 
two drinks per day. Drinking at these levels usually is not associated with 
health risks and can help to prevent certain forms of heart disease. 
But did you know that even moderate drinking, under certain circumstances, is 
not risk free? And that if you drink at more than moderate levels, you may be 
putting yourself at risk for serious problems with your health and problems with 
family, friends, and coworkers? This booklet explains some of the consequences 
of drinking that you may not have considered. 
 
  
   
    What Is a Drink 
     
    A standard drink is:
    
     - One 12-ounce bottle of beer* 
 or wine cooler 
      - One 5-ounce glass of wine 
     
 - 1.5 ounces of 80-proof 
 distilled spirits. 
     
      
    *Beer ranges considerably in its alcohol content,  with malt liquor being higher in its alcohol content  than most other brewed beverages. 
    | 
  
 

Drinking and Driving 
It may surprise you to learn that you don't need to drink much alcohol before 
your ability to drive becomes impaired. For example, certain driving 
skills--such as steering a car while, at the same time, responding to changes in 
traffic--can be impaired by blood alcohol concentrations (BACs) as low as 0.02 
percent. (The BAC refers to the amount of alcohol in the blood.) A 160-pound man 
will have a BAC of about 0.04 percent 1 hour after consuming two 12-ounce beers 
or two other standard drinks on an empty stomach (see the box, "What Is a 
Drink?"). And the more alcohol you consume, the more impaired your driving 
skills will be. Although most States set the BAC limit for adults who drive 
after drinking at 0.08 to 0.10 percent, impairment of driving skills begins at 
much lower levels.
Interactions With Medications 
Alcohol interacts negatively with more than 150 medications. For example, if 
you are taking antihistamines for a cold or allergy and drink alcohol, the 
alcohol will increase the drowsiness that the medication alone can cause, making 
driving or operating machinery even more hazardous. And if you are taking large 
doses of the painkiller acetaminophen and drinking alcohol, you are risking 
serious liver damage. Check with your doctor or pharmacist before drinking any 
amount of alcohol if you are taking any over-the-counter or prescription 
medications. 
Interpersonal Problems 
The more heavily you drink, the greater the potential for problems at home, 
at work, with friends, and even with strangers. These problems may include: 
 - Arguments with or estrangement from your spouse and other family members; 
 
 - Strained relationships with coworkers; 
 
 - Absence from or lateness to work with increasing frequency; 
 
 - Loss of employment due to decreased productivity; and 
 
 - Committing or being the victim of violence. 
 
 
Alcohol-Related Birth Defects 
If you are a pregnant woman or one who is trying to conceive, you can prevent 
alcohol-related birth defects by not drinking alcohol during your pregnancy. 
Alcohol can cause a range of birth defects, the most serious being fetal alcohol 
syndrome (FAS). Children born with alcohol-related birth defects can have 
lifelong learning and behavior problems. Those born with FAS have physical 
abnormalities, mental impairment, and behavior problems. Because scientists do 
not know exactly how much alcohol it takes to cause alcohol-related birth 
defects, it is best not to drink any alcohol during this time. 

Long-Term Health Problems 
Some problems, like those mentioned above, can occur after drinking over a 
relatively short period of time. But other problems--such as liver disease, 
heart disease, certain forms of cancer, and pancreatitis--often develop more 
gradually and may become evident only after long-term heavy drinking. Women may 
develop alcohol-related health problems after consuming less alcohol than men do 
over a shorter period of time. Because alcohol affects many organs in the body, 
long-term heavy drinking puts you at risk for developing serious health 
problems, some of which are described below. 
Alcohol-related liver disease. More than 2 million Americans suffer 
from alcohol-related liver disease. Some drinkers develop alcoholic hepatitis, 
or inflammation of the liver, as a result of long-term heavy drinking. Its 
symptoms include fever, jaundice (abnormal yellowing of the skin, eyeballs, and 
urine), and abdominal pain. Alcoholic hepatitis can cause death if drinking 
continues. If drinking stops, this condition often is reversible. About 10 to 20 
percent of heavy drinkers develop alcoholic cirrhosis, or scarring of the liver. 
Alcoholic cirrhosis can cause death if drinking continues. Although cirrhosis is 
not reversible, if drinking stops, one's chances of survival improve 
considerably. Those with cirrhosis often feel better, and the functioning of 
their liver may improve, if they stop drinking. Although liver transplantation 
may be needed as a last resort, many people with cirrhosis who abstain from 
alcohol may never need liver transplantation. In addition, treatment for the 
complications of cirrhosis is available. 
Heart disease. Moderate drinking can have beneficial effects on the 
heart, especially among those at greatest risk for heart attacks, such as men 
over the age of 45 and women after menopause. But long-term heavy drinking 
increases the risk for high blood pressure, heart disease, and some kinds of 
stroke. 
Cancer. Long-term heavy drinking increases the risk of developing 
certain forms of cancer, especially cancer of the esophagus, mouth, throat, and 
voice box. Women are at slightly increased risk of developing breast cancer if 
they drink two or more drinks per day. Drinking may also increase the risk for 
developing cancer of the colon and rectum. 
Pancreatitis. The pancreas helps to regulate the body's blood sugar 
levels by producing insulin. The pancreas also has a role in digesting the food 
we eat. Long-term heavy drinking can lead to pancreatitis, or inflammation of 
the pancreas. This condition is associated with severe abdominal pain and weight 
loss and can be fatal. 
____________________________
If you or someone you know has been drinking heavily, there is a risk of 
developing serious health problems. Because some of these health problems are 
both reversible and treatable, it is important to see your doctor for help. Your 
doctor will be able to advise you about both your health and your drinking. 
Research Directions 
The National Institute on Alcohol Abuse and Alcoholism (NIAAA), National 
Institutes of Health, supports about 90 percent of the Nation's research on 
alcohol use and related consequences. Through this research, NIAAA and the 
researchers it supports make an implicit promise--that alcohol research will 
yield practical applications that will help those who suffer as a result of 
alcohol abuse and alcoholism. Today, alcohol researchers are working on the 
cutting edge of medical science to answer questions such as: 
 - Who is at risk for alcohol-related problems? 
 
 - How does alcohol affect the body, including the brain? 
 
 - How is the risk for alcoholism inherited? 
 
 - What are the health benefits and risks of moderate drinking? 
 
 - What therapies, including medications, show promise for treating alcohol dependence more effectively? 
 
 
Each new discovery made by alcohol researchers provides a piece of the answer 
to the ages old question of how to prevent and treat the alcohol-related 
troubles that plague individuals, families, and society. We see the future of 
alcohol research both as a challenge and as a reward: A challenge, because with 
more answers come more questions, and we still have far to go. A reward, because 
the answers we find ultimately will help diminish a public health threat that 
has existed for far too long.
If you or someone you know needs help or more information, contact: 
  - Al-Anon Family Group Headquarters
1600 Corporate Landing 
  Parkway
Virginia Beach, VA 23454-5617
Internet address: 
  http://www.al-anon.alateen.org 
  Makes referrals to local Al-Anon groups, which are support groups for 
  spouses and other significant adults in an alcoholic person's life. Also makes 
  referrals to Alateen groups, which offer support to children of 
  alcoholics. 
  
    - Locations of Al-Anon or Alateen meetings worldwide can be obtained by 
    calling 1-888-4AL-ANON Monday through Friday, 8 a.m.-6 p.m. (e.s.t.). 
    
 - Free informational materials can be obtained by calling the toll-free 
    numbers (operating 7 days per week, 24 hours per day): 
    
 - U.S.: (800) 356-9996 
    
 - Canada: (800) 714-7498
 
   - Alcoholics Anonymous (AA) World Services
475 Riverside Drive, 
  11th Floor
New York, NY 10115
(212) 870-3400
Internet address: 
  http://www.alcoholics-anonymous.org 
  Makes referrals to local AA groups and provides informational materials 
  on the AA program. Many cities and towns also have a local AA office listed in 
  the telephone book. 
   - National Council on Alcoholism and Drug Dependence (NCADD)
12 
  West 21st Street
New York, NY 10010
(800) NCA-CALL
Internet address: 
  http://www.ncadd.org 
  Provides telephone numbers of local NCADD affiliates (who can provide 
  information on local treatment resources) and educational materials on 
  alcoholism via the above toll-free number. 
   - National Institute on Alcohol Abuse and Alcoholism
Scientific 
  Communications Branch
6000 Executive Boulevard, Suite 409
Bethesda, MD 
  20892-7003
(301) 443-3860
Internet address: http://www.niaaa.nih.gov 
  Makes available free publications on all aspects of alcohol abuse and 
  alcoholism. Many are available in Spanish.  Call, write, or search the 
  World Wide Web site for a list of publications and ordering information. 
  
  
   
  NIH Publication No. 99-4323
Printed 1999